1. Drug development – pre-registration phases of clinical trials. Post-registration drug monitoring. Types and design of clinical trials. Bioequivalence studies. Clinical significance of pharmacokinetic parameters. Clinically relevant interactions at the metabolism level: mechanism, significance and examples. Clinically significant interactions: sources of information, a therapeutic approach in avoiding adverse interactions. Pharmacovigilance. Importance of monitoring drug side … Настави са читањем Exam questions